Eco-Balance - friendly probiotic bacteria for a balanced aquarium environment and core system health. Research has demonstrated that friendly probiotic bacteria are key to maintaining a balanced, stress-free aquarium environment. The normal processes in a reef aquarium upset this balance and allow unfriendly bacteria and algae to dominate. Many good bacteria are removed by the protein skimmer. This can negatively affect water quality and overall fish health. Eco-Balance uses friendly probiotic bacteria as a natural way to restore and maintain a balanced aquarium environment while enhancing the immune response of saltwater fish. With specific probiotics against several species of Vibrio Eco-Balance reduces the numbers of bad bacteria in your aquarium resulting in a clean, healthy, less-stressful environment. For reef and nano aquaria. 16-Ounce treats 480-gallon.